Canon or no, Fresno is the ideal location to base a company of assassins, which is what I'm presuming the D (as in destroy) are. One thing people who live there say about the place is you can easily get anywhere from there. It's centrally located in California, so Ukiah, Petaluma, LA, are all a pretty easy day trip. There is a major airport, and many private airports, so it's easy to fly. You can also easily catch a bus or a train should the need arise.
Since Fresno is a hotbead of gang and other criminal activities - one of the highest crime rates in the country - if you behave halfway respectably and don't make waves, you won't get any trouble from law enforcement. It's easy to be invisible there. Basing this story in Fresno, is just one more thing that makes it really well thought out and believable for me.
It's pretty clear the canon story has assassins on both sides. Warpylol blew up brother's car, supposedly with the help of Gemma, and Brother offed Gemma under Tachyon's direction - although we have yet to see a body.
So who would be based in Fresno - Brother? Warpylol? - either or, both and?
Given the plausibility, it seems worth considering.
Ok all you Fresnans, don't jump on my case - you know it's true
